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The potential underpinning processes leading to unexpected intragenomic variation have been discussed in a number of studies, but a comprehensive understanding remains to be determined. Amplicon sequencing of partial regions of the ribosomal rna loci (rdna) is widely used to profile microbial communities Three species of sponges, axinella aruensis, phakellia sp
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And acanthella cavernosa, were selected to investigate the extent of intragenomic variation (igv) in the internal transcribed. In this work, we summarize information on variation or polymorphisms in rdnas across a wide range of taxa amongst animals, fungi, plants, and protists. The high intragenomic variation in the its rdna observed in the present study can be attributed to the divergence of multiple copies that have not been homogenized through concerted evolution or similar forces.